Comparison of high sensitive c reactive protein levels between metabolically healthy and unhealthy obese

Authors

  • I Made Pande Dwipayana Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar
  • I Made Siswadi Semadi Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar
  • Ida Bagus Aditya Nugraha Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar
  • Wira Gotera Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar
  • Made Ratna Saraswati Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar
  • Anak Agung Gede Budhiarta Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar
  • Ketut Suastika Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

DOI:

https://doi.org/10.36216/jpd.v8i1.235

Keywords:

hs-CRP, MHO, MUHO

Abstract

Introduction: Overweight and obesity are associated with risks of several comorbidities, yet not all individuals with obesity condition having equal metabolic risks, suggesting the presence of a subgroup known as metabolically healthy obese (MHO) and metabolically unhealthy obese (MUHO). Obesity is characterized by chronic low-grade inflammation, with C-reactive Protein (CRP) serving as a key inflammatory marker. Research on high-sensitivity CRP (hs-CRP) levels across different obesity categories, especially MHO and MUHO, remains limited.

Aim: This study aims to compare hs-CRP levels across various levels of obesity, particularly in MHO and MUHO individuals.

Methods: This analytical cross-sectional study included subjects aged 18-60 from Denpasar with a BMI over 25 kg/m2. Subjects with chronic or acute inflammatory conditions were excluded. Comparative tests were utilized for analysis.

Results: The study comprised 40 men and 20 women with an average age of 35.6 years. Of these, 35% were classified as MHO and 65% as MUHO. The analysis revealed no significant difference in hs-CRP levels between the MHO and MUHO groups (p = 0.108), likely due to similar age and BMI distributions resulting in comparable levels of inflammation.

Conclusion: The analysis demonstrated no significant variation in hs-CRP levels between MHO and MUHO groups.

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Author Biographies

  • I Made Pande Dwipayana, Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

  • I Made Siswadi Semadi, Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

  • Ida Bagus Aditya Nugraha, Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

  • Wira Gotera, Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

  • Made Ratna Saraswati, Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

  • Anak Agung Gede Budhiarta, Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

  • Ketut Suastika, Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Udayana University/ Prof. dr. I Goesti Ngoerah Gde Ngoerah Hospital Denpasar

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Published

2024-05-01

How to Cite

1.
Comparison of high sensitive c reactive protein levels between metabolically healthy and unhealthy obese. Udayana In. Med. [Internet]. 2024 May 1 [cited 2024 Jul. 16];8(1):32-5. Available from: https://www.jpdunud.org/index.php/JPD/article/view/235