Sequential organ failure assessment (SOFA) score as a predictor of acute kidney injury in COVID-19 patients: a systematic review and meta-analysis

Authors

  • Nicolas Daniel Widjanarko Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Erich Tamio Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Steven Alvianto Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Nadhea Debrinita Surya Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Rexel Kuatama Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia
  • Maria Riastuti Iryaningrum Department of Internal Medicine, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

DOI:

https://doi.org/10.36216/jpd.v7i1.206

Keywords:

AKI, COVID-19, SOFA score, predictor

Abstract

Background: The sequential organ failure assessment (SOFA) score is a tool used to describe organ failure in critically ill patients. Studies have showed that coronavirus disease 2019 (COVID-19) patients who develop predictor of acute kidney injury (AKI) often have an increased SOFA. 

Objective: This study aimed to evaluate the potential of SOFA score as a predictor AKI in COVID-19 patients. 

Methods: A systematic search was conducted on PubMed, Google Scholar, EBSCO-Host, and ProQuest. The risk of bias was assessed using the Newcastle-Ottawa Scale . 

Result: Out of the 9 studies reviewed, 7 showed a significant association between SOFA score and AKI. The meta-analysis of 3 studies gave mean differences of 1.66 in favor of the AKI group (95% CI 1.12 - 2.21). The heterogeneity was low (Tau2 result = 0.06, I2 result = 22% with p = 0.28) and the significant results for the overall effect showed a value of p < 0.00001. 

Conclusion: The SOFA score has the potential to be a good predictor of AKI development in COVID-19 patients, with a significant mean difference.

Downloads

Download data is not yet available.

Author Biographies

  • Nicolas Daniel Widjanarko, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Erich Tamio, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Steven Alvianto, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Nadhea Debrinita Surya, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Rexel Kuatama, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

  • Maria Riastuti Iryaningrum, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

    Department of Internal Medicine, Faculty of Medicine and Health Sciences, Atma Jaya Catholic University of Indonesia, Jakarta, Indonesia

References

Wu YC, Chen CS, Chan YJ. The outbreak of COVID-19: An overview. J Chin Med Assoc. 2020;83(3):217–220.

Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;382(18):1708–1720.

Hirsch JS, Ng JH, Ross DW, et al. Acute kidney injury in patients hospitalized with COVID-19. Kidney Int. 2020;98(1):209.

Dhama K, Khan S, Tiwari R, et al. Coronavirus Disease 2019–COVID-19. Clin Microbiol Rev. 2020;33(4):e00028-20.

Tzotzos SJ, Fischer B, Fischer H, et al. Incidence of ARDS and outcomes in hospitalized patients with COVID-19: a global literature survey. Crit Care. 2020;24(1):516.

Panitchote A, Mehkri O, Hastings A, et al. Factors associated with acute kidney injury in acute respiratory distress syndrome. Ann Intensive Care. 2019;9(1):74.

Lin W, Hu L, Zhang Y, et al. Single-cell analysis of ACE2 expression in human kidneys and bladders reveals a potential route of 2019-nCoV infection. bioRxiv. 2020;2020.02.08.939892.

Kant S, Menez SP, Hanouneh M, et al. The COVID-19 nephrology compendium: AKI, CKD, ESKD and transplantation. BMC Nephrol. 2020;21(1):449.

Diao B, Wang C, Wang R, et al. Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 infection. Nat Commun. 2021;12(1):2506.

Ahmadian E, Hosseiniyan Khatibi SM, Razi Soofiyani S, et al. Covid-19 and kidney injury: Pathophysiology and molecular mechanisms. Rev Med Virol. 2021;31(3):e2176.

Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med. 1996;22(7):707–710.

Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016;315(8):801–810.

Lee CW, Kou HW, Chou HS, et al. A combination of SOFA score and biomarkers gives a better prediction of septic AKI and in-hospital mortality in critically ill surgical patients: a pilot study. World J Emerg Surg WJES. 2018;13:41.

Joseph A, Zafrani L, Mabrouki A, et al. Acute kidney injury in patients with SARS-CoV-2 infection. Ann Intensive Care. 2020;10(1):117.

Cui X, Yu X, Wu X, et al. Acute kidney injury in patients with the coronavirus disease 2019: a multicenter study. Kidney Blood Press Res. 2020;45(4):612–622.

Rubin S, Orieux A, Prevel R, et al. Characterization of acute kidney injury in critically ill patients with severe coronavirus disease 2019. Clin Kidney J. 2020;13(3):354–361.

Xu J, Xie J, Du B, et al. Clinical characteristics and outcomes of patients with severe COVID-19 induced acute kidney injury. J Intensive Care Med. 2020;885066620970858.

Xia P, Wen Y, Duan Y, et al. Clinicopathological features and outcomes of acute kidney injury in critically ill COVID-19 with prolonged disease course: a retrospective cohort. J Am Soc Nephrol. 2020;31(9):2205–2221.

Wang F, Ran L, Qian C, et al. Epidemiology and outcomes of acute kidney injury in COVID-19 patients with acute respiratory distress syndrome: a multicenter retrospective study. Blood Purif. 2021;50(4-5):499–505.

Alfano G, Ferrari A, Fontana F, et al; Modena Covid-19 Working Group (MoCo19). Incidence, risk factors and outcome of acute kidney injury (AKI) in patients with COVID-19. Clin Exp Nephrol. 2021;25(11):1203-1214.

Molina Barragan AM, Pardo E, Galichon P, et al. SARS-CoV-2 renal impairment in critical care: an observational study of 42 cases (Kidney COVID). J Clin Med. 2021;10(8):1571.

Zhang X, Guo W, Hua J, et al. The incidence, risk factors and clinical outcomes of acute kidney injury in critically ill patients with COVID-19: a multicenter study. Rochester, NY: Social Science Research Network; 2020 Apr [cited 2021 Jan 5]. Report No.: ID 3572908. Available from: https://papers.ssrn.com/abstract=3572908

Gilbert A, Robertson L, Heron JE, et al. Risk factors for development of acute kidney injury in hospitalised adults in Zimbabwe. PloS One. 2020;15(10):e0241229.

Cartin-Ceba R, Kashiouris M, Plataki M, et al. Risk factors for development of acute kidney injury in critically ill patients: a systematic review and meta-analysis of observational studies. Crit Care Res Pract. 2012;2012:691013.

Singh P, Rifkin DE, Blantz RC. Chronic kidney disease: an inherent risk factor for acute kidney injury?. Clin J Am Soc Nephrol. 2010;5(9):1690–1695.

Hsu RK, Hsu CY. The role of acute kidney injury in chronic kidney disease. Semin Nephrol. 2016;36(4):283–292.

Kellum JA, Lameire N, Aspelin P, et al. Kidney disease: improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney Int Suppl. 2012;2(1):1–138.

Downloads

Published

2023-06-09

How to Cite

1.
Sequential organ failure assessment (SOFA) score as a predictor of acute kidney injury in COVID-19 patients: a systematic review and meta-analysis. Udayana In. Med. [Internet]. 2023 Jun. 9 [cited 2024 May 11];7(1):19-26. Available from: https://www.jpdunud.org/index.php/JPD/article/view/206

Similar Articles

1-10 of 20

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 > >>